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Study: HT may affect symptom load and quality of life unrelated to hypothyroidism

August 27, 2017

Johannes Ott and colleagues from Kaiserin Elisabeth Spital and Medical University of Vienna, Austria, report that women with higher levels of anti-thyroid antibody had a significantly higher number of symptoms, even though their levels of thyroid-stimulating hormone (TSH)-a measure of thyroid function-did not differ from TSH levels measured in women with lower antibody levels. In the article, "Hashimoto's Thyroiditis Affects Symptom Load and Quality of Life Unrelated to Hypothyroidism: A Prospective Case-Control Study in Women Undergoing Thyroidectomy for Benign Goiter (liebertpub/contentframe.aspx?code=nh31x7M2VXcDkUK2yLHKgCdvvaMD4fwLwbhPWLtSBQ7GuKZ1Y8ps%2fbmdWZnnT%2b5hK2kGHsnNkBQaXFUbDGq7K%2ftEIICjCaMhvPRq8RfrJXo%3d)," the authors conclude that hypothyroidism is only one factor contributing to HT symptoms.

"This study raises important clinical issues. Although the authors did not study thyroid hormone treatment for Hashimoto's thyroiditis, it raises the possibility that optimal doses of thyroid hormone will not completely ameliorate all symptoms. Further studies are required to confirm the findings of Ott et al. and to determine if patients with hypothyroidism due to Hashimoto's thyroiditis still have residual symptoms despite achieving an ideal biochemical response to thyroid hormone replacement therapy," says Charles H. Emerson, MD, Editor-in-Chief of Thyroid and Professor Emeritus of Medicine at the University of Massachusetts School of Medicine, in Worcester.

Source: Mary Ann Liebert, Inc./Genetic Engineering News