Scientists develop algorithm to predict gene sequence of kinases

March 31, 2017

"Protein kinases are well recognized by the pharmaceutical and biotech industry as highly productive targets for drug development with application to over 400 human diseases," commented Dr. Steven Pelech, President and Chief Scientific Officer of Kinexus and a professor in the Department of Medicine at the University of British Columbia. "Cancer, diabetes, Alzheimer's disease are just a few of many examples of disorders that arise from miscommunication in cell signalling systems. PhosphoNET is a valuable tool to guide biomedical researchers in fruitful directions to define biomarkers for disease diagnosis and kinase drug targets for development of new treatments."

Dr. Pelech added "We are extremely excited by the prospect that our kinase specificity prediction algorithm can be applied to rapidly elucidate the complex structures of protein kinase-based communications systems for any animal, plant or microbes for which their genome has been or will be sequenced. The high definition maps of protein phosphorylation networks that Kinexus can now produce could steer a significant portion of biomedical research over the next decade."

SOURCE Kinexus Bioinformatics Corporation