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New positive data on Generex Oral-lyn published in Diabetes, Obesity and Metabolism

July 30, 2017

The study demonstrates that treatment with Generex Oral-lyn?? is a simple and valuable therapy for reducing post-prandial hyperglycaemia in obese subjects with IGT.  Importantly, the treatment is safe and no subject experienced hypoglycaemia.  Professor Pozzilli commented that:  "The results of this study are of particular interest because they demonstrate that Generex Oral-lyn?? could be successfully employed to normalize post-prandial glucose levels in subjects with IGT.  The convenience of buccal absorption of insulin in subjects with IGT may represent a significant advantage in terms of therapeutic compliance."

Dr. James Anderson, a member of the Generex Scientific Advisory Board, noted that "This study is the first demonstration of directly increasing first phase insulin levels and reducing post prandial glucose using a non-invasive therapy.  The potential to use Generex Oral-lyn?? as a frontline treatment for patients with IGT could have far reaching implications.  If such a non-invasive therapy delayed the onset of diabetes along with all of its complications, it could eventually become a cost effective alternative to allowing the condition to progress with just diet and exercise."

As a result of these important findings, a second trial (Prevoral 2) is underway where subjects with IGT are being treated for six months with either (a) Generex Oral-lyn?? + diet and exercise, or (b) the standard IGT treatment of only diet and exercise.  The end-point of the Prevoral 2 study is represented by glycated haemoglobin values.  Initial promising data were presented in September at the 46th Congress of the European Association of the Study of Diabetes in Stockholm, Sweden.  Final results of the Prevoral 2 study will be available in mid-2011.

SOURCE Generex Biotechnology Corporation